Name | CHITOSAN HYDROCHLORIDE |
Synonyms | Chitosan HCl CHITOSAN HYDROCHLORIDE Poliglusam hydrochloride Chitosan hydrochloride,M.W.50000 |
CAS | 70694-72-3 |
EINECS | 207-451-4 |
Molecular Formula | C14H27ClN2O11 |
Molar Mass | 434.824 |
Solubility | Sparingly soluble in water, practically insoluble in anhydrous ethanol. |
Appearance | White powder |
Storage Condition | 2-8°C |
Reference Show more | 1. [IF=10.588] Jun Qian et al."Prussian blue analogue functionalized magnetic microgels with ionized chitosan for the cleaning of cesium-contaminated clay."J Hazard Mater. 2020 Mar;386:121965 2. [IF=6.953] Hongcai Zhang et al."Enhanced antibacterial activity of lysozyme loaded quaternary ammonium chitosan nanoparticles functionalized with cellulose nanocrystals."Int J Biol Macromol. 2021 Nov;191:71 3. [IF=6.843] Tingting Wu et al."Strontium-substituted hydroxyapatite grown on graphene oxide nanosheet-reinforced chitosan scaffold to promote bone regeneration."Biomater Sci-Uk. 2020 Aug;8(16):4603-4615 4. [IF=4.384] Tao Zhu et al."Analgesic and antipruritic effects of oxymatrine sustained-release microgel cream in a mouse model of inflammatory itch and pain."Eur J Pharm Sci. 2020 Jan;141:105110 5. [IF=6.4] Dan Zhao et al."Screening of Chitosan Derivatives-Carbon Dots Based on Antibacterial Activity and Application in Anti-Staphylococcus aureus Biofilm."Int J Nanomed. 2022 Mar;17:937-952 6. [IF=10.435] Wang Jie et al."Field application of nanoliposomes delivered quercetin by inhibiting specific hsp70 gene expression against plant virus disease."J Nanobiotechnol. 2022 Dec;20(1):1-16 |
Overview | chitosan is widely present in the nature of lower animals, plants, such as arthropods (shrimp, crab) chitin in the Shell as a raw material, by adding alkali, heating deacetylation reaction. This product is non-toxic to the human body and will not cause secondary pollution to the environment. Therefore, it is widely used in water treatment, food, medicine and agriculture. In water treatment, it is mainly used as polyelectrolyte coagulant, sludge dewatering aid and water purification agent. |
Use | in food processing, as a flocculant in the clarification of fruit juice products, can promote solid-liquid separation, removal of fruit acids and suspended solid particles from cloudy fruit juices increases transparency and improves product quality and grade. In the pharmaceutical industry, it is used as an antibacterial agent, an anticoagulant, an antiviral agent, an anticancer agent, a hemostatic agent, a dialysis membrane, and the like. In agriculture, it is used as a feed additive, a plant pathogen antibacterial agent, a plant seed surface covering agent, and the like. Chitosan hydrochloride, which can be directly dissolved in water, is a strong cationic chitosan derivative, and is expected to be a drug carrier under mild preparation conditions. it can be used for hydrophilic drugs, food and health care, pharmaceutical dressing and carriers, etc. |
Application | chitosan hydrochloride as a medical dressing class has the following effects: antibacterial, promoting wound healing, hemostasis, absorption of wound exudate, etc. At the same time, chitosan can be degraded into natural metabolites by lysozyme in vivo, which is non-toxic and can be completely absorbed by organisms. However, because chitosan is insoluble in water, it can only have contact antibacterial effect, and can not act well on the inside of the wound, which greatly limits its application in the medical field. |